On the Road Again

Nancy Zacherl was an active 59-year-old who was always on the move — playing with her grandchildren, going for one of her daily three-mile walks or riding a motorcycle with her husband. One morning, Nancy suddenly felt a searing pain in her back. She struggled to continue with her daily routine, but her back pain was so intense and constant that it rendered the once-active Nancy incapable of even getting out of bed. A remarkable new and minimally invasive technology, however, got Nancy back on her feet and on the road again.

Nancy’s doctor determined her back pain was a result of osteoporosis, a disease in which bones become fragile and break easily. More than 44 million Americans have osteoporosis, 80 percent of whom are women. Osteoporosis is often called the “silent disease” because it sets in without any symptoms, as was the case with Nancy, but then a strain, bump or fall can cause a bone fracture.

Osteoporosis Incapacitates Nancy

After a magnetic resonance imaging (MRI) diagnostic scan, Nancy’s doctor discovered that her osteoporosis had caused one of her spinal bones to collapse. These fractures cause severe back pain, and over time can lead to a loss of height or the development of a hump. Because it has a compression effect on the lungs and internal organs, the fracture often makes it difficult to eat, sleep and walk, as well as causing other serious symptoms. As Nancy explains, “One of the worst parts about the pain was it even made it hard to catch my breath.”

Osteoporosis-related fractures exact a huge toll on a patient's quality of life and the healthcare system, costing the United States healthcare system more than $18 billion a year — a figure that is expected to grow dramatically as the population ages. Estimates are not available for the cost of osteoporosis in terms of lost work days, productivity and disability.

Osteoporosis: The Silent Disease
Number of Americans with osteoporosis44 million over age 501
Osteoporosis-caused fractures1.5 million fractures annually1
  • 700,000 spine
  • 300,000 hip
  • 250,000 wrist
  • 300,000 other site
Annual costs$18 billion in direct U.S. medical costs1



New, Minimally Invasive Procedures to Treat Osteoporosis

Fortunately, Nancy’s doctor recommended using a novel procedure to fix her broken vertebra and help restore her life. This minimally invasive treatment for spinal fractures involves inserting two compressed balloons into the vertebral body through a pair of slender tubes. The balloons are inflated to create a cavity in the vertebral body and restore vertebral body height. The balloons are then deflated and removed, and the vertebral cavity is filled with bone cement that acts as an “internal cast,” stabilizing the fracture. Nancy received the treatment and was back on her feet within a day of the surgery.

Aside from this procedure, called kyphoplasty, physicians also can choose a similar minimally invasive treatment, called vertebroplasty, to treat vertebral compression fractures. Given the delicate nature of spinal surgery, there are instances where one approach is superior to the other.

Before these minimally invasive therapies, vertebral compression fractures were treated with narcotic pain medication, bed rest, bracing and physical therapy. Unfortunately, these treatment options do not restore spinal alignment, can exacerbate osteoporosis-related problems and often rob patients of their mobility, deteriorating their quality of life. Over the past twenty years, however, there have been significant improvements made to the traditional surgical procedures in terms of costs, recovery time and success rates.

Medical Technology Gets Patients Back on Track

Studies show that individuals with primary osteoporosis-related compression fractures experienced reduced pain, suffered fewer new vertebral fractures and needed fewer back-pain-related doctors’ visits a year after the kyphoplasty procedure.2 Kyphoplasty also has been shown to provide immediate and sustained improvements in function and mobility for patients and a significant improvement in their quality of life.3

Immediately after the procedure was performed, Nancy said she could “finally breathe again!” Although her physician insisted on taking every precaution, Nancy was able to take an extended motorcycle tour with her husband just days after surgery. Today, Nancy is working at a local flower shop and has started taking her three-mile walks again. It has been five years since her treatment, and she has not experienced any back pain or additional fractures. “My back has gotten even stronger over the years,” said Nancy.

Improvements in Treatments of Compression Spinal Fractures4
Traditional Back SurgeryMinimally Invasive Procedure
Incision size4-8 cm1-2 cm
Recovery time4-6 weeks or longerLess than 7 days
Procedure timeTypically 2-3 hoursTypically 1 hour
Hospital length of stayTypically 3-4 daysTypically 1-2 days
Procedure costOn average $12,000 – $20,000On average $9,000 – $14,000




  1. National Osteoporosis Foundation. “Incidence and Economic Burden of Osteoporotic Fractures in the United States, 2005-2025.” http://nof.confex.com/nof/2005/techprogram/P400.HTM (28 April 2006).
  2. Grafe IA, Da Fonseca K, Hillmeier J, et al. “Reduction of pain and fracture incidence after kyphoplasty: 1-year outcomes of a prospective controlled trial of patients with primary osteoporosis.” Osteoporosis International 16(12) (2005):2005-12.
  3. Ledlie JT, Renfro MB. “Kyphoplasty Treatment of Vertebral Fractures: 2-Year Outcomes Show Sustained Benefits.” Spine 31 (2006):57-64.
  4. Industry estimates. 2006.


Nancy recovered from painful spinal fracture due to osteoporosis after a minimally invasive procedure. Read more on how advanced technology improves lives.
Value: Medical technology lowers social costs by getting people back to work and life. Dependability: Using the highest safety standards, medical technology improves patient outcomes. Innovation: The unique interaction between patients, physicians, medical innovators and legislative champions drives breakthroughs in medical technology.